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Symptoms of Cryopyrin-Associated Periodic Syndromes (CAPS)

Effects of Familial Cold Autoinflammatory Syndrome (FCAS) and Muckle-Wells Syndrome on Patients

Debilitating and recurrent symptoms of CAPS can disable patients for hours or last for days.1

  • Without a proper diagnosis, lack of proper treatment can leave patients suffering

CAPS can remain undiagnosed and untreated due to the rarity of the disease and the resemblance of symptoms to other conditions.1,2

  • While symptoms may resemble other illnesses, CAPS symptoms are chronic in nature.1,2

Although rare, you may have a CAPS patient in your practice. Use the following chart of chronic symptoms of CAPS and the downloadable assessment below to help you identify undiagnosed patients in your practice.

Once diagnosed, effective treatment can help to relieve the signs and symptoms of CAPS.

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Symptoms of CAPS1-3

Symptoms of CAPS

CAPS Signs and Symptoms Assessment

A brief assessment that can be referenced in-office when seeing patients. If a patient experiences any of these signs or symptoms on an ongoing basis, a diagnosis of CAPS may be considered.

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References:

  • 1. Toker O, Hashkes PJ. Prevalence of Cryopyrin-Associated Periodic Syndrome (CAPS) Biologics. 2010;4:131-138.
  • 2. Hoffman HM. Hereditary immunologic disorders caused by pyrin and cryopyrin. Curr Allergy Asthma Rep. 2007;7:323-330.
  • 3. Hawkins PN, Lachmann HJ, Aganna E, Dermott MF. Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra. Arthritis Rheum. 2004;50:607-612.


isi-Professional www.fda.gov/medwatch full prescribing information