Is ILARIS^® Right for You?

ILARIS^®—A Specific Treatment for CAPS (Cryopyrin-Associated Periodic Syndrome)

CAPS is a group of rare, genetic diseases that include FCAS (Familial Cold Autoinflammatory Syndrome) and Muckle-Wells Syndrome (MWS).

Although there may be only about 300 patients with a rare, genetic condition called CAPS in the United States, experts believe that not all patients with CAPS have been diagnosed yet because of poor disease recognition.

• Symptoms of CAPS may resemble other conditions: however in CAPS, symptoms are chronic in nature and keep coming back

Take this quiz to see if your symptoms are like those of patients with FCAS or MWS.

• Do you experience one of these symptoms on a regular basis or in response to changes in temperature or environment?
• Rash on an ongoing basis
• Fever or chills on an ongoing basis
• In addition to ongoing rash and/or fever/chills, do you regularly have 1 or more of the following?
• Headache or migraine
• Fatigue
• Sore or red eyes
• Muscle or joint pain
• Has any family member reported similar symptoms or received a diagnosis of CAPS?

If so, speak to your doctor to see if you have CAPS. (Learn more about CAPS in the section Facts About CAPS .)

Only a physician can determine whether you have CAPS, so be sure to discuss all symptoms with your doctor.

• Download the Talking to Your Doctor Discussion Guide for a few simple suggestions to start a conversation with your doctor about CAPS

ILARIS^® may be right for you or others you care for if:

• A diagnosis by a physician has been made for:
• Familial Cold Autoinflammatory Syndrome (FCAS)
• Muckle-Wells Syndrome (MWS)
• You or the patient is aged 4 years and older

In clinical studies of patients diagnosed with CAPS who were taking ILARIS^®:

• 97% of patients had Complete Response within the first treatment period (8 weeks)
• The majority of patients (71%) had Complete Response in just 7 days

Complete response was measured by lab results and by the doctor's evaluation of the patient's skin disease and symptoms as being minimal or better, including symptoms such as rash, fatigue, muscle pain, headache or migraine, sore or red eyes, and joint pain.

If you know or care for someone who has CAPS, visit the section For Parents and Other Caregivers to learn what you can do to help.