Answers to Your Questions About TRAPS and ILARIS
Answers to Your Questions About TRAPS and ILARIS
What is Tumor Necrosis Factor Receptor Associated Periodic Syndrome (TRAPS)?
TRAPS is an inherited, rare, and serious condition belonging to a group of diseases called Periodic Fever Syndromes. Like other types of Periodic Fevers, TRAPS is an autoinflammatory condition that can cause attacks, or flares, which result in symptoms including fevers, rash, pain, inflammation, abdominal pain, musculoskeletal pain, and/or eye irritations.
What causes TRAPS?
TRAPS is an inherited disease that is caused by the genetic mutation of the TNFRSF1A (Tumor Necrosis Factor Receptor Super Family 1A) gene. When this happens, it can lead to inflammation and other TRAPS symptoms.
How long will my child have TRAPS?
There is no cure for TRAPS, but with continuous treatment, children with TRAPS may experience symptom improvement.
What are Periodic Fever Syndromes?
Periodic Fever Syndromes are a group of rare, autoinflammatory diseases characterized by a range of symptoms, including but not limited to recurrent fevers, rash, pain, and joint inflammation. Periodic Fevers are typically inherited from other family members, but can occur on their own. Periodic Fevers can affect both children and adults, though symptoms usually begin during childhood.
Is TRAPS contagious?
TRAPS is not contagious. It's an inherited disease, which means that it can be passed down from other family members, although the disease can occur on its own. Certain factors are thought to trigger TRAPS flares, including stress, immunizations, and intense physical activity.
What will happen to my child with TRAPS?
TRAPS can vary from child to child. In some patients, the symptoms of TRAPS diminish with age. You should keep track of your child's TRAPS symptoms, and be sure to know about possible disease triggers. Learn about TRAPS treatment options.
What is ILARIS?
ILARIS® is a prescription medication that is FDA approved to treat TRAPS. ILARIS works by attaching to and blocking interleukin-1 beta (IL-1β), a type of cytokine responsible for inflammation. ILARIS is given once a month as a subcutaneous injection right below the skin.
How can ILARIS help with TRAPS?
ILARIS helps provide fast and sustained relief from TRAPS. In a study of 22 patients with TRAPS, 45.5% had minimal to no disease activity at day 15 through week 16. Study participants were assessed and given a single physician score based on several signs and symptoms, including: skin rash, musculoskeletal pain, abdominal pain, and eye manifestations.
Is ILARIS given intravenously?
ILARIS is not given as an intravenous infusion (infused inside a vein over a period of time). Instead, it is given as a subcutaneous (right under the skin) injection, once a month by a doctor or nurse. A home health nurse can be sent to your home to administer ILARIS to your child. If you are eligible, this service and other ILARIS support opportunities may be available for your child.
Is support available to help us pay for ILARIS?
We're committed to helping you get access to ILARIS. Our representatives work with you and your child's doctor to help you get started, including:
Contacting your insurance company
Verifying insurance benefits and investigation of coverage
Addressing coverage issues
Assisting with prior authorization and appeals, if needed
Providing co-pay* assistance for eligible patients with commercial insurance
Providing information about alternative assistance options for uninsured patients
*Limitations apply. Please contact the ILARIS Support Program at 866-972-8315 for more information.
Who can I speak to if I have more questions about ILARIS?
Talk to your child's pediatric rheumatologist or other healthcare professional. Your child's TRAPS treatment team can consist of many important members. Make sure that you find a doctor that you and your child are both comfortable with.
