A – Z
Z – A
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Adult-Onset Still's Disease:
AOSD is an autoinflammatory disorder which can be caused by having too much of or being too sensitive to certain proteins, including IL-1β, and can lead to symptoms such as fever, rash, headache, feeling very tired (fatigue), or painful joints and muscles. AOSD is a type of Still's disease that develops after 16 years of age.
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Arthritis:
inflammation of one or more joints, which can cause pain, swelling, stiffness, and loss of motion.
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Autoinflammatory disease:
an illness in which the body's control of inflammation is not functioning properly, leading to uncontrolled inflammation.
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Biologic:
a product made from living cells that is used to treat diseases.
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Cytokine:
a protein produced by the body that interacts with the cells of the immune system to help fight infection. When the body produces too much of a cytokine, it can cause inflammation and tissue destruction.
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Flare:
the worsening and increase in severity of disease symptoms.
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Idiopathic:
the exact cause of the disease is unknown.
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Immune system:
the body's natural defense system that protects against any material foreign to the body.
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Inflammation:
the body's protective response that results in heat, pain, redness, and swelling.
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Injection:
usually referred to as "a shot," an injection puts medication into the body using a syringe.
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Interleukin-1 beta (IL-1β):
a type of cytokine that plays a key role in the body's inflammatory response.
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Juvenile Arthritis (JA):
a medical condition that occurs in children under the age of 16, and involves swelling in one or more joints lasting at least 6 weeks.
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Rheumatologist:
a doctor who specializes in treating patients with rheumatic diseases, including arthritis, many autoimmune diseases, and many autoinflammatory diseases.
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Quotidian Fevers:
fevers that repeat on a daily basis.
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Rare disease:
an uncommon illness that affects very few people.
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Still's disease:
Still's disease is an autoinflammatory disorder which can be caused by having too much of or being too sensitive to certain proteins, including interleukin-1β (IL-1β), and can lead to symptoms such as fever, rash, headache, feeling very tired (fatigue), or painful joints and muscles. If your symptoms begin when you're under 16, your diagnosis will be Systemic Juvenile Idiopathic Arthritis (SJIA). If your symptoms begin after you're 16, your diagnosis will be Adult-Onset Still's Disease (AOSD).
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Symptoms:
a description of the way you are feeling due to an illness.
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Systemic:
affecting the entire body, rather than a single organ or body part.
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Systemic Juvenile Idiopathic Arthritis (SJIA):
SJIA is an autoinflammatory disorder which can be caused by having too much of or being too sensitive to certain proteins, including IL-1β, and can lead to symptoms such as fever, rash, headache, feeling very tired (fatigue), or painful joints and muscles. SJIA is a type of Still's disease.
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