What is Hyperimmunoglobulin D Syndrome/Mevalonate Kinase Deficiency (HIDS/MKD)?
HIDS/MKD is an inherited and rare condition belonging to a group of diseases called Periodic Fever Syndromes. Like other types of Periodic Fevers, HIDS/MKD is an autoinflammatory condition that can cause attacks or flares.
What causes HIDS/MKD?
How long will my child have HIDS/MKD?
There is no cure for HIDS/MKD, but with continuous treatment, children with HIDS/MKD may experience symptom improvement.
What are Periodic Fever Syndromes?
Periodic Fever Syndromes are a group of rare, autoinflammatory diseases characterized by a range of symptoms, including but not limited to recurrent fevers, rash, pain, and joint inflammation. Periodic Fevers are typically inherited from family members, but can occur on their own. Periodic Fevers can affect both children and adults, though symptoms usually begin during childhood.
Is HIDS/MKD contagious?
HIDS/MKD is not contagious. It's an inherited disease, which means that it can be passed down from family members, although the disease can occur on its own. Certain factors are thought to trigger HIDS/MKD flares, including stress, immunizations, and infections.
What will happen to my child with HIDS/MKD?
HIDS/MKD can vary from child to child. You should keep track of your child's HIDS/MKD symptoms, and be sure to know about possible disease triggers. Learn about HIDS/MKD treatment options.
What is ILARIS?
ILARIS® is a prescription medication that is FDA approved to treat HIDS/MKD. ILARIS works by attaching to and blocking interleukin-1 beta (IL-1β), a type of cytokine responsible for inflammation. For HIDS/MKD, ILARIS is given once a month as a subcutaneous injection right below the skin.
How can ILARIS help with HIDS/MKD?
ILARIS helps provide fast and sustained relief from HIDS/MKD. In a study of 37 patients with HIDS/MKD, 35.1% had minimal to no disease activity at day 15 through week 16. Study participants were assessed for their CRP measurements and given a single physician's global assessment (PGA) score based on several signs and symptoms, including swollen lymph nodes (lymphadenopathy), canker sores (aphthous ulcers), and abdominal pain.
Is ILARIS given intravenously?
ILARIS is not given as an intravenous infusion (infused inside a vein over a period of time). Instead, it is given as a subcutaneous (right under the skin) injection by a doctor or nurse. A home health nurse can be sent to your home to administer ILARIS to your child. If you are eligible, this service and other ILARIS support options may be available for your child.
Is support available to help us pay for ILARIS?
We're committed to helping you get access to ILARIS. Our ILARIS Companion representatives are here to help by working with your doctor or your child's doctor, and:
Contacting your insurance company
Verifying insurance benefits and investigation of coverage
Addressing coverage issues
Navigating prior authorization and appeals, if needed
Providing co-pay* assistance for eligible patients with commercial insurance
Providing information about alternative assistance options for uninsured patients
*Limitations apply. Please contact ILARIS Companion at 866-972-8315 for more information.