Glossary

A – Z

Z – A

Print SJIA glossary terms
  • Arthritis:

    inflammation of one or more joints, which can cause pain, swelling, stiffness, and loss of motion.

  • Autoinflammatory disease:

    an illness in which the body's control of inflammation is not functioning properly, leading to uncontrolled inflammation.

  • Biologic:

    a product made from living cells that is used to treat diseases.

  • Cytokine:

    a protein produced by the body that interacts with the cells of the immune system to help fight infection. When the body produces too much of a cytokine, it can cause inflammation and tissue destruction.

  • Flare:

    the worsening and increase in severity of disease symptoms.

  • Idiopathic:

    the exact cause of the disease is unknown.

  • Immune system:

    the body's natural defense system that protects against any material foreign to the body.

  • Inflammation:

    the body's protective response that results in heat, pain, redness, and swelling.

  • Injection:

    usually referred to as "a shot," an injection puts medication into the body using a syringe.

  • Interleukin-1 beta (IL-1β):

    a type of cytokine that plays a key role in the body's inflammatory response.

  • Juvenile Arthritis (JA):

    a medical condition that occurs in children under the age of 16, and involves swelling in one or more joints lasting at least 6 weeks.

  • Pediatric rheumatologist:

    a doctor who specializes in treating children and adolescents with rheumatic diseases, including arthritis, many autoimmune diseases, and many autoinflammatory diseases.

  • Quotidian Fevers:

    fevers that repeat on a daily basis.

  • Rare disease:

    an uncommon illness that affects very few people.

  • Still's disease:

    Still's Disease is an autoinflammatory disorder which can be caused by having too much of or being too sensitive to certain proteins, including interleukin-1b (IL-1b), and can lead to symptoms such as fever, rash, headache, feeling very tired (fatigue), or painful joints and muscles. Still's disease is referred to as Adult-Onset Still's Disease (AOSD) in adults, and Systemic Juvenile Idiopathic Arthritis (SJIA) in children.

  • Symptoms:

    a description of the way you are feeling due to an illness.

  • Systemic:

    affecting the entire body, rather than a single organ or body part.

  • Systemic Juvenile Idiopathic Arthritis:

    SJIA is an autoinflammatory disorder which can be caused by having too much of or being too sensitive to certain proteins, including IL-1β, and can lead to symptoms such as fever, rash, headache, feeling very tired (fatigue), or painful joints and muscles. SJIA is a type of Still's disease.